NAV1.7 Voltage-Gated Sodium Channel MeSH Descriptor Data 2023

MeSH Heading: NAV1.7 Voltage-Gated Sodium Channel
Tree Number(s): D12.776.157.530.400.875.750.700; D12.776.543.550.450.875.750.700; D12.776.543.585.400.875.750.700; D12.776.631.960.700
Unique ID: D062556
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D062556
Scope Note: A voltage-gated sodium channel subtype found widely expressed in nociceptive primary sensory neurons. Defects in the SCN9A gene, which codes for the alpha subunit of this sodium channel, are associated with several pain sensation-related disorders.
Entry Term(s): Peripheral Sodium Channel 1; SCN9A Sodium Channel alpha Subunit; Type 9 Voltage-Gated Sodium Channel; Voltage-Gated Sodium Channel Type 9; Voltage-Gated Sodium Channel Type 9 Subunit alpha
Registry Number: 0
Previous Indexing: Sodium Channels (1989-2012)
See Also: Erythromelalgia
Public MeSH Note: 2013
History Note: 2013
Entry Combination: agonists:Voltage-Gated Sodium Channel Agonists; antagonists & inhibitors:Voltage-Gated Sodium Channel Blockers
Date Established: 2013/01/01
Date of Entry: 2012/07/03
Revision Date: 2016/07/01

Entry Combination: agonists:Voltage-Gated Sodium Channel Agonists; antagonists & inhibitors:Voltage-Gated Sodium Channel Blockers
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Membrane Transport Proteins [D12.776.157.530]
      - Ion Channels [D12.776.157.530.400]
        
        Sodium Channels [D12.776.157.530.400.875]
        
        Voltage-Gated Sodium Channels [D12.776.157.530.400.875.750]
        
        NAV1.1 Voltage-Gated Sodium Channel [D12.776.157.530.400.875.750.100]
        
        NAV1.2 Voltage-Gated Sodium Channel [D12.776.157.530.400.875.750.200]
        
        NAV1.3 Voltage-Gated Sodium Channel [D12.776.157.530.400.875.750.300]
        
        NAV1.4 Voltage-Gated Sodium Channel [D12.776.157.530.400.875.750.400]
        
        NAV1.5 Voltage-Gated Sodium Channel [D12.776.157.530.400.875.750.500]
        
        NAV1.6 Voltage-Gated Sodium Channel [D12.776.157.530.400.875.750.600]
        
        NAV1.7 Voltage-Gated Sodium Channel [D12.776.157.530.400.875.750.700]
        
        NAV1.8 Voltage-Gated Sodium Channel [D12.776.157.530.400.875.750.800]
        
        NAV1.9 Voltage-Gated Sodium Channel [D12.776.157.530.400.875.750.900]
        
        Voltage-Gated Sodium Channel beta Subunits [D12.776.157.530.400.875.750.960]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Ion Channels [D12.776.543.550.450]
        
        Sodium Channels [D12.776.543.550.450.875]
        
        Voltage-Gated Sodium Channels [D12.776.543.550.450.875.750]
        
        NAV1.1 Voltage-Gated Sodium Channel [D12.776.543.550.450.875.750.100]
        
        NAV1.2 Voltage-Gated Sodium Channel [D12.776.543.550.450.875.750.200]
        
        NAV1.3 Voltage-Gated Sodium Channel [D12.776.543.550.450.875.750.300]
        
        NAV1.4 Voltage-Gated Sodium Channel [D12.776.543.550.450.875.750.400]
        
        NAV1.5 Voltage-Gated Sodium Channel [D12.776.543.550.450.875.750.500]
        
        NAV1.6 Voltage-Gated Sodium Channel [D12.776.543.550.450.875.750.600]
        
        NAV1.7 Voltage-Gated Sodium Channel [D12.776.543.550.450.875.750.700]
        
        NAV1.8 Voltage-Gated Sodium Channel [D12.776.543.550.450.875.750.800]
        
        NAV1.9 Voltage-Gated Sodium Channel [D12.776.543.550.450.875.750.900]
        
        Voltage-Gated Sodium Channel beta Subunits [D12.776.543.550.450.875.750.970]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Transport Proteins [D12.776.543.585]
      - Ion Channels [D12.776.543.585.400]
        
        Sodium Channels [D12.776.543.585.400.875]
        
        Voltage-Gated Sodium Channels [D12.776.543.585.400.875.750]
        
        NAV1.1 Voltage-Gated Sodium Channel [D12.776.543.585.400.875.750.100]
        
        NAV1.2 Voltage-Gated Sodium Channel [D12.776.543.585.400.875.750.200]
        
        NAV1.3 Voltage-Gated Sodium Channel [D12.776.543.585.400.875.750.300]
        
        NAV1.4 Voltage-Gated Sodium Channel [D12.776.543.585.400.875.750.400]
        
        NAV1.5 Voltage-Gated Sodium Channel [D12.776.543.585.400.875.750.500]
        
        NAV1.6 Voltage-Gated Sodium Channel [D12.776.543.585.400.875.750.600]
        
        NAV1.7 Voltage-Gated Sodium Channel [D12.776.543.585.400.875.750.700]
        
        NAV1.8 Voltage-Gated Sodium Channel [D12.776.543.585.400.875.750.800]
        
        NAV1.9 Voltage-Gated Sodium Channel [D12.776.543.585.400.875.750.900]
        
        Voltage-Gated Sodium Channel beta Subunits [D12.776.543.585.400.875.750.970]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Nerve Tissue Proteins [D12.776.631]
    - Voltage-Gated Sodium Channels [D12.776.631.960]

NAV1.7 Voltage-Gated Sodium Channel Preferred

Concept UI: M0568601
Registry Number: 0
Scope Note: A voltage-gated sodium channel subtype found widely expressed in nociceptive primary sensory neurons. Defects in the SCN9A gene, which codes for the alpha subunit of this sodium channel, are associated with several pain sensation-related disorders.
Terms: NAV1.7 Voltage-Gated Sodium Channel Preferred Term
Term UI T813390
Date11/29/2011
LexicalTag ABX
ThesaurusID NLM (2013); Voltage-Gated Sodium Channel Type 9
Term UI T813392
Date11/29/2011
LexicalTag NON
ThesaurusID NLM (2013); Peripheral Sodium Channel 1
Term UI T813807
Date12/05/2011
LexicalTag NON
ThesaurusID NLM (2013); Type 9 Voltage-Gated Sodium Channel
Term UI T813391
Date11/29/2011
LexicalTag NON
ThesaurusID NLM (2013)

Voltage-Gated Sodium Channel Type 9 Subunit alpha Narrower

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