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NAV1.2 Voltage-Gated Sodium Channel MeSH Descriptor Data 2023


MeSH Heading
NAV1.2 Voltage-Gated Sodium Channel
Tree Number(s)
D12.776.157.530.400.875.750.200
D12.776.543.550.450.875.750.200
D12.776.543.585.400.875.750.200
D12.776.631.960.200
Unique ID
D062551
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D062551
Scope Note
A voltage-gated sodium channel subtype that mediates the sodium ion permeability of excitable membranes. Defects in the SCN2A gene which codes for the alpha subunit of this sodium channel are associated with benign familial infantile seizures type 3, and early infantile epileptic encephalopathy type 11.
Entry Term(s)
NAV1.2 alpha Subunit
SCN2A Sodium Channel alpha Subunit
Sodium Channel Protein Type 2 Subunit alpha
Sodium Channel, Voltage-Gated, Type II, alpha 1
Sodium Channel, Voltage-Gated, Type II, alpha 1 Subunit
Type 2 Voltage-Gated Sodium Channel
Voltage-Gated Sodium Channel Type 2
Voltage-Gated Sodium Channel Type 2 Subunit alpha
Voltage-Gated Sodium Channel Type 2 alpha Subunit
Registry Number
0
Previous Indexing
Sodium Channels (1989-2012)
Public MeSH Note
2013
History Note
2013
Entry Combination
agonists:Voltage-Gated Sodium Channel Agonists
antagonists & inhibitors:Voltage-Gated Sodium Channel Blockers
Date Established
2013/01/01
Date of Entry
2012/07/03
Revision Date
2016/07/01
NAV1.2 Voltage-Gated Sodium Channel Preferred
Voltage-Gated Sodium Channel Type 2 Subunit alpha Narrower
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