NLM Logo

NAV1.5 Voltage-Gated Sodium Channel MeSH Descriptor Data 2025


MeSH Heading
NAV1.5 Voltage-Gated Sodium Channel
Tree Number(s)
D12.776.157.530.400.875.750.500
D12.776.543.550.450.875.750.500
D12.776.543.585.400.875.750.500
D12.776.631.960.500
Unique ID
D062554
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D062554
Scope Note
A voltage-gated sodium channel subtype that mediates the sodium ion PERMEABILITY of CARDIOMYOCYTES. Defects in the SCN5A gene, which codes for the alpha subunit of this sodium channel, are associated with a variety of CARDIAC DISEASES that result from loss of sodium channel function.
Entry Term(s)
SCN5A Sodium Channel alpha Subunit
Sodium Channel Protein Type 5 Subunit alpha
Sodium Channel, Voltage-Gated, Type V, alpha Subunit
Type 5 Voltage-Gated Sodium Channel
Voltage-Gated Na+ Channel Na(v)1.5a
Voltage-Gated Sodium Channel Type 5
Voltage-Gated Sodium Channel Type 5 Subunit alpha
Previous Indexing
Sodium Channels (2002-2012)
Public MeSH Note
2013; SODIUM CHANNEL PROTEIN TYPE 5 SUBUNIT ALPHA (now NAV1.5 VOLTAGE-GATED SODIUM CHANNEL) was indexed under SODIUM CHANNELS 2002-2012
History Note
2013
Entry Combination
agonists:Voltage-Gated Sodium Channel Agonists
antagonists & inhibitors:Voltage-Gated Sodium Channel Blockers
Date Established
2013/01/01
Date of Entry
2012/07/03
Revision Date
2016/07/01
NAV1.5 Voltage-Gated Sodium Channel Preferred
Voltage-Gated Sodium Channel Type 5 Subunit alpha Narrower
page delivered in 0.138s