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p300-CBP Transcription Factors MeSH Descriptor Data 2023


MeSH Heading
p300-CBP Transcription Factors
Tree Number(s)
D08.811.913.050.134.415.500.575
D12.776.930.680
Unique ID
D050880
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D050880
Scope Note
A family of histone acetyltransferases that is structurally-related to CREB-BINDING PROTEIN and to E1A-ASSOCIATED P300 PROTEIN. They function as transcriptional coactivators by bridging between DNA-binding TRANSCRIPTION FACTORS and the basal transcription machinery. They also modify transcription factors and CHROMATIN through ACETYLATION.
Entry Term(s)
p300-CBP Coactivator
p300-CBP Protein
Registry Number
EC 2.3.1.48
Public MeSH Note
2006; P300/CBP PROTEINS was indexed under NUCLEAR PROTEINS & TRANS-ACTIVATORS 1999-2005
History Note
2006(1994)
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2015/12/02
p300-CBP Transcription Factors Preferred
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