MeSH Browser

MeSH Heading: Sigma Factor
Tree Number(s): D12.776.930.800
Unique ID: D012808
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D012808
Annotation: a transcription factor; /‌biosyn /‌physiol permitted
Scope Note: A protein which is a subunit of RNA polymerase. It effects initiation of specific RNA chains from DNA.
Entry Term(s): Minor Sigma Factor; RNA Polymerase Sigma Factor H; Sigma Element; Sigma Initiation Factor; Sigma Subunit
Previous Indexing: Bacterial Proteins (1973-1976); Proteins (1966-1976); Transcription, Genetic (1973-1976)
Public MeSH Note: 91; was see under TRANSCRIPTION FACTORS 1977-90
History Note: 91(77); was see under TRANSCRIPTION FACTORS 1977-90
Date Established: 1991/01/01
Date of Entry: 1976/04/19
Revision Date: 2005/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0019833
Scope Note: A protein which is a subunit of RNA polymerase. It effects initiation of specific RNA chains from DNA.
Terms: Sigma Factor Preferred Term
Term UI T037773
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1977); Sigma Element
Term UI T037772
Date05/11/1987
LexicalTag NON
ThesaurusID UNK (19XX); Sigma Initiation Factor
Term UI T037774
Date04/16/1976
LexicalTag NON
ThesaurusID UNK (19XX); Sigma Subunit
Term UI T037775
Date04/16/1976
LexicalTag NON
ThesaurusID UNK (19XX)

Sigma Factor MeSH Descriptor Data 2025