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Genes, rel MeSH Descriptor Data 2022


MeSH Heading
Genes, rel
Tree Number(s)
G05.360.340.024.340.375.500.791.552
Unique ID
D020573
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D020573
Scope Note
Family of retrovirus-associated DNA sequences (v-rel) originally isolated from an avian reticuloendotheliosis virus strain. The proto-oncogene rel (c-rel) codes for a subcellular (nuclear and cytoplasmic) transcription factor that has a role in lymphocyte differentiation. Translocation or overexpression of c-rel or competition from v-rel causes oncogenesis. The human rel gene is located at 2p12-13 on the short arm of chromosome 2.
Entry Term(s)
c-rel Genes
c-rel Proto-Oncogenes
rel Genes
rel Oncogene
v-rel Genes
v-rel Oncogenes
Previous Indexing
Genes, Viral (1983-1999)
Oncogenes (1983-1999)
See Also
Oncogene Proteins v-rel
Proto-Oncogene Proteins c-rel
Public MeSH Note
2000; see ONCOGENES 1988-1999
History Note
2000; use ONCOGENES 1988-1999
Date Established
2000/01/01
Date of Entry
1999/11/03
Revision Date
2008/07/08
Genes, rel Preferred
c-rel Genes Narrower
v-rel Genes Narrower
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