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Genes, sis MeSH Descriptor Data 2025


MeSH Heading
Genes, sis
Tree Number(s)
G05.360.340.024.340.375.500.791.560
Unique ID
D020571
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D020571
Scope Note
Retrovirus-associated DNA sequences (v-sis) originally isolated from the simian sarcoma virus (SSV). The proto-oncogene c-sis codes for a growth factor which is the B chain of PLATELET-DERIVED GROWTH FACTOR. v-sis or overexpression of c-sis causes tumorigenesis. The human sis gene is located at 22q12.3-13.1 on the long arm of chromosome 22.
Entry Term(s)
Genes, PDGFB
c-sis Genes
c-sis Proto-Oncogenes
sis Genes
sis Oncogene
v-sis Genes
v-sis Oncogenes
Previous Indexing
Oncogenes (1983-1999)
See Also
Oncogene Proteins v-sis
Proto-Oncogene Proteins c-sis
Public MeSH Note
2000; see ONCOGENES 1988-1999
History Note
2000; use ONCOGENES 1988-1999
Date Established
2000/01/01
Date of Entry
1999/11/03
Revision Date
2008/07/08
Genes, sis Preferred
v-sis Genes Narrower
c-sis Genes Narrower
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