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Genes, abl MeSH Descriptor Data 2022


MeSH Heading
Genes, abl
Tree Number(s)
G05.360.340.024.340.375.500.791.100
Unique ID
D016313
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016313
Annotation
abl stands for "ABelson Leukemia"
Scope Note
Retrovirus-associated DNA sequences (abl) originally isolated from the Abelson murine leukemia virus (Ab-MuLV). The proto-oncogene abl (c-abl) codes for a protein that is a member of the tyrosine kinase family. The human c-abl gene is located at 9q34.1 on the long arm of chromosome 9. It is activated by translocation to bcr on chromosome 22 in chronic myelogenous leukemia.
Entry Term(s)
abl Genes
abl Oncogene
bcr-abl Proto-Oncogenes
bcr-v-abl Oncogenes
c-abl Genes
c-abl Proto-Oncogenes
v-abl Genes
v-abl Oncogenes
Previous Indexing
Oncogenes (1982-1990)
See Also
Fusion Proteins, bcr-abl
Oncogene Proteins v-abl
Proto-Oncogene Proteins c-abl
Public MeSH Note
91
History Note
91
Date Established
1991/01/01
Date of Entry
1990/06/28
Revision Date
2008/07/08
Genes, abl Preferred
bcr-v-abl Oncogenes Broader
abl Oncogene Narrower
bcr-abl Proto-Oncogenes Broader
c-abl Genes Narrower
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