MeSH Browser

MeSH Heading: Genes, abl
Tree Number(s): G05.360.340.024.340.375.500.791.100
Unique ID: D016313
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D016313
Annotation: abl stands for "ABelson Leukemia"
Scope Note: Retrovirus-associated DNA sequences (abl) originally isolated from the Abelson murine leukemia virus (Ab-MuLV). The proto-oncogene abl (c-abl) codes for a protein that is a member of the tyrosine kinase family. The human c-abl gene is located at 9q34.1 on the long arm of chromosome 9. It is activated by translocation to bcr on chromosome 22 in chronic myelogenous leukemia.
Entry Term(s): abl Genes; abl Oncogene; bcr-abl Proto-Oncogenes; bcr-v-abl Oncogenes; c-abl Genes; c-abl Proto-Oncogenes; v-abl Genes; v-abl Oncogenes
Previous Indexing: Oncogenes (1982-1990)
See Also: Fusion Proteins, bcr-abl; Oncogene Proteins v-abl; Proto-Oncogene Proteins c-abl
Public MeSH Note: 91
History Note: 91
Date Established: 1991/01/01
Date of Entry: 1990/06/28
Revision Date: 2008/07/08

Allowable Qualifiers: drug effects (DE)

ethics (ES)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Genes, abl MeSH Descriptor Data 2023