MeSH Browser

MeSH Heading: MAP Kinase Kinase Kinase 2
Tree Number(s): D08.811.913.696.620.682.700.559.200; D12.776.476.563.554.200
Unique ID: D048730
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D048730
Scope Note: A 70-kDa MAP kinase kinase kinase with specificity for MAP KINASE KINASE 5. It is activated during the cellular response to GROWTH FACTORS, oxidative stress, and hyperosmotic conditions.
Entry Term(s): MAP3K2 Protein Kinase; MEK Kinase 2; MEKK-2 Protein Kinase; MEKK2 Protein; MEKK2 Protein Kinase
Registry Numbers: EC 2.7.11.25
Previous Indexing: MAP Kinase Kinase Kinases (1999-2004)
Public MeSH Note: 2005; MAP KINASE KINASE KINASE 2 was indexed under MAP KINASE KINASE KINASES 1999-2004
History Note: 2005(1999)
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0350337
Registry Numbers: EC 2.7.11.25
Scope Note: A 70-kDa MAP kinase kinase kinase with specificity for MAP KINASE KINASE 5. It is activated during the cellular response to GROWTH FACTORS, oxidative stress, and hyperosmotic conditions.
Terms: MAP Kinase Kinase Kinase 2 Preferred Term
Term UI T576712
Date03/12/2004
LexicalTag ACX
ThesaurusID NLM (2005); MAP3K2 Protein Kinase
Term UI T576715
Date03/12/2004
LexicalTag ACX
ThesaurusID NLM (2005); MEKK-2 Protein Kinase
Term UI T581331
Date04/06/2004
LexicalTag ACX
ThesaurusID NLM (2005); MEKK2 Protein
Term UI T400466
Date11/19/1999
LexicalTag ACX
ThesaurusID NLM (2005); MEK Kinase 2
Term UI T576713
Date03/12/2004
LexicalTag ACX
ThesaurusID NLM (2005); MEKK2 Protein Kinase
Term UI T576714
Date03/12/2004
LexicalTag ACX
ThesaurusID NLM (2005)

MAP Kinase Kinase Kinase 2 MeSH Descriptor Data 2025