MeSH Browser

MeSH Heading: MAP Kinase Kinase Kinase 1
Tree Number(s): D08.811.913.696.620.682.700.559.100; D12.776.476.563.554.100
Unique ID: D048728
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D048728
Scope Note: A 195-kDa zinc finger motif-containing MAP kinase kinase kinase with broad specificity for MAP KINASE KINASES. It localizes to the CYTOSKELETON and can activate a variety of MAP kinase-dependent pathways.
Entry Term(s): MAP ERK Kinase Kinase 1; MAP3K1 Protein; MEK Kinase 1; MEKK-1 Protein Kinase; MEKK1 Protein; MEKK1 Protein Kinase; Mitogen-Activated Protein Kinase Kinase Kinase 1
Previous Indexing: Mitogen-Activated Protein Kinase Kinase Kinases (2004); Protein-Serine-Threonine Kinases (1994-2004)
See Also: Zinc Fingers
Public MeSH Note: 2005; MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 1 was indexed under MAP KINASE KINASE KINASES 2004 & under PROTEIN-SERINE-THREONINE KINASES 1994-2004
History Note: 2005(1994)
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0233961
Scope Note: A 195-kDa zinc finger motif-containing MAP kinase kinase kinase with broad specificity for MAP KINASE KINASES. It localizes to the CYTOSKELETON and can activate a variety of MAP kinase-dependent pathways.
Terms: MAP Kinase Kinase Kinase 1 Preferred Term
Term UI T576698
Date03/12/2004
LexicalTag ACX
ThesaurusID NLM (2005); MEKK1 Protein
Term UI T263965
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2005); Mitogen-Activated Protein Kinase Kinase Kinase 1
Term UI T571971
Date02/09/2004
LexicalTag NON
ThesaurusID NLM (2005); MEK Kinase 1
Term UI T576699
Date03/12/2004
LexicalTag ACX
ThesaurusID NLM (2005); MEKK1 Protein Kinase
Term UI T576700
Date03/12/2004
LexicalTag ACX
ThesaurusID NLM (2005); MAP3K1 Protein
Term UI T581327
Date04/06/2004
LexicalTag ACX
ThesaurusID NLM (2005); MAP ERK Kinase Kinase 1
Term UI T263963
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2005); MEKK-1 Protein Kinase
Term UI T581328
Date04/06/2004
LexicalTag ACX
ThesaurusID NLM (2005)

MAP Kinase Kinase Kinase 1 MeSH Descriptor Data 2025