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Receptor-Interacting Protein Serine-Threonine Kinases MeSH Descriptor Data 2026
A family of serine-threonine kinases that plays a role in intracellular signal transduction by interacting with a variety of signaling adaptor proteins such as CRADD SIGNALING ADAPTOR PROTEIN; TNF RECEPTOR-ASSOCIATED FACTOR 2; and TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN. Although they were initially described as death domain-binding adaptor proteins, members of this family may contain other protein-binding domains such as those involving caspase activation and recruitment.
Entry Term(s)
RIP (Receptor Interacting Protein)
RIP Serine-Threonine Kinase
RIP Serine-Threonine Kinases
RIPK (Ribosome Inactivating Proteins)
RIPK Ribosome Inactivating Proteins
Receptor Interacting Protein RIP
Receptor-Interacting Protein Serine-Threonine Kinase 1
Receptor-Interacting Protein Serine-Threonine Kinase 3
Registry Numbers
EC 2.7.11.1
EC 2.7.11.1
EC 2.7.11.1
Public MeSH Note
2007; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES was indexed under PROTEIN-SERINE THREONINE KINASES & TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PROTEINS 2006, & under PROTEINS 1995-2006
A family of serine-threonine kinases that plays a role in intracellular signal transduction by interacting with a variety of signaling adaptor proteins such as CRADD SIGNALING ADAPTOR PROTEIN; TNF RECEPTOR-ASSOCIATED FACTOR 2; and TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN. Although they were initially described as death domain-binding adaptor proteins, members of this family may contain other protein-binding domains such as those involving caspase activation and recruitment.