Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

Receptor-Interacting Protein Serine-Threonine Kinases MeSH Descriptor Data 2026


MeSH Heading
Receptor-Interacting Protein Serine-Threonine Kinases
Tree Number(s)
D08.811.913.696.620.682.700.801
D12.776.157.057.018.400
D12.776.157.057.500.186
D12.776.476.024.320.662
D12.776.476.024.500.186
D12.776.476.075.421.400
D12.776.476.563.801
Unique ID
D053422
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053422
Scope Note
A family of serine-threonine kinases that plays a role in intracellular signal transduction by interacting with a variety of signaling adaptor proteins such as CRADD SIGNALING ADAPTOR PROTEIN; TNF RECEPTOR-ASSOCIATED FACTOR 2; and TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN. Although they were initially described as death domain-binding adaptor proteins, members of this family may contain other protein-binding domains such as those involving caspase activation and recruitment.
Entry Term(s)
RIP (Receptor Interacting Protein)
RIP Serine-Threonine Kinase
RIP Serine-Threonine Kinases
RIPK (Ribosome Inactivating Proteins)
RIPK Ribosome Inactivating Proteins
Receptor Interacting Protein RIP
Receptor-Interacting Protein Serine-Threonine Kinase 1
Receptor-Interacting Protein Serine-Threonine Kinase 3
Registry Numbers
EC 2.7.11.1
EC 2.7.11.1
EC 2.7.11.1
Public MeSH Note
2007; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES was indexed under PROTEIN-SERINE THREONINE KINASES & TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PROTEINS 2006, & under PROTEINS 1995-2006
History Note
2007(1995)
Date Introduced
2007/01/01
Last Updated
2026/01/01
Receptor-Interacting Protein Serine-Threonine Kinases Preferred
Receptor-Interacting Protein Serine-Threonine Kinase 1 Narrower
Receptor-Interacting Protein Serine-Threonine Kinase 3 Narrower
page delivered in 0.155s