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I-kappa B Kinase MeSH Descriptor Data 2023


MeSH Heading
I-kappa B Kinase
Tree Number(s)
D08.811.913.696.620.682.700.494
D12.776.476.563.494
Unique ID
D051550
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D051550
Scope Note
A protein serine-threonine kinase that catalyzes the PHOSPHORYLATION of I KAPPA B PROTEINS. This enzyme also activates the transcription factor NF-KAPPA B and is composed of alpha and beta catalytic subunits, which are protein kinases and gamma, a regulatory subunit.
Entry Term(s)
CHUK Kinase
Conserved Helix-Loop-Helix Ubiquitous Kinase
I Kappa B alpha-Associated Protein Kinase
I kappa B Kinase
IKBKB
IKK 1 Kinase
IKK 2 Kinase
IKK alpha
IKK beta
IKK epsilon
IKK gamma
IKKepsilon
IkappaB Kinase
IkappaB Kinase alpha
IkappaB Kinase beta
IkappaB Kinase epsilon
IkappaB Kinase gamma
IkappaBalpha Kinase
NF-kappaB Essential Modifier
NK-kappa B-Activating Kinase NAK
Registry Number
EC 2.7.11.10
Related Numbers
EC 2.7.11.10
See Also
I-kappa B Proteins
Public MeSH Note
2006; I-KAPPA B KINASE was indexed under PROTEIN-SERINE-THREONINE KINASES 1997-2005
History Note
2006(1997)
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2021/05/21
I-kappa B Kinase Preferred
IkappaB Kinase epsilon Narrower
IkappaB Kinase gamma Narrower
IkappaB Kinase alpha Narrower
IkappaB Kinase beta Narrower
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