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3-Phosphoinositide-Dependent Protein Kinases MeSH Descriptor Data 2026
Highly conserved protein-serine threonine kinases that phosphorylate and activate a group of AGC protein kinases, especially in response to the production of the SECOND MESSENGERS, phosphatidylinositol 3,4,-biphosphate (PtdIns(3,4)P2) and phosphatidylinositol 3,4,5-triphosphate (PtdIns(3,4,5)P3).
Entry Term(s)
3-Phosphoinositide Dependent Protein Kinase-1
3-Phosphoinositide Dependent Protein Kinase-2
3-Phosphoinositide-Dependent Kinase 1 (PDK1)
3-Phosphoinositide-Dependent Protein Kinase
3-Phosphoinositide-Dependent Protein Kinase-1
3-Phosphoinositide-Dependent Protein Kinase-2
PtdIns(3,4,5)P3-Dependent Protein Kinase-1
Registry Numbers
EC 2.7.11.1
EC 2.7.11.1
EC 2.7.11.1
Related Numbers
EC 2.7.11.1
Previous Indexing
Protein-Serine-Threonine Kinases (1997-2013)
Public MeSH Note
2014; 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE was indexed under PROTEIN-SERINE-THREONINE KINASES 1997-2013
Highly conserved protein-serine threonine kinases that phosphorylate and activate a group of AGC protein kinases, especially in response to the production of the SECOND MESSENGERS, phosphatidylinositol 3,4,-biphosphate (PtdIns(3,4)P2) and phosphatidylinositol 3,4,5-triphosphate (PtdIns(3,4,5)P3).