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3-Phosphoinositide-Dependent Protein Kinases MeSH Descriptor Data 2025


MeSH Heading
3-Phosphoinositide-Dependent Protein Kinases
Tree Number(s)
D08.811.913.696.620.682.700.745
D12.776.476.563.745
Unique ID
D064413
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D064413
Scope Note
Highly conserved protein-serine threonine kinases that phosphorylate and activate a group of AGC protein kinases, especially in response to the production of the SECOND MESSENGERS, phosphatidylinositol 3,4,-biphosphate (PtdIns(3,4)P2) and phosphatidylinositol 3,4,5-triphosphate (PtdIns(3,4,5)P3).
Entry Term(s)
3-Phosphoinositide Dependent Protein Kinase-1
3-Phosphoinositide Dependent Protein Kinase-2
3-Phosphoinositide-Dependent Kinase 1 (PDK1)
3-Phosphoinositide-Dependent Protein Kinase
3-Phosphoinositide-Dependent Protein Kinase-1
3-Phosphoinositide-Dependent Protein Kinase-2
PtdIns(3,4,5)P3-Dependent Protein Kinase-1
Related Numbers
EC 2.7.11.1
Previous Indexing
Protein-Serine-Threonine Kinases (1997-2013)
Public MeSH Note
2014; 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE was indexed under PROTEIN-SERINE-THREONINE KINASES 1997-2013
History Note
2014
Date Established
2014/01/01
Date of Entry
2013/07/08
Revision Date
2021/05/20
3-Phosphoinositide-Dependent Protein Kinases Preferred
3-Phosphoinositide Dependent Protein Kinase-1 Narrower
3-Phosphoinositide Dependent Protein Kinase-2 Narrower
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