Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

Second Messenger Systems MeSH Descriptor Data 2026


MeSH Heading
Second Messenger Systems
Tree Number(s)
G02.111.820.800
G04.835.800
Unique ID
D015290
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015290
Annotation
a metab concept; IM; coord with substance acting as the second messenger (IM) with /‌physiol or /‌antag as applicable
Scope Note
Systems in which an intracellular signal is generated in response to an intercellular primary messenger such as a hormone or neurotransmitter. They are intermediate signals in cellular processes such as metabolism, secretion, contraction, phototransduction, and cell growth. Examples of second messenger systems are the adenyl cyclase-cyclic AMP system, the phosphatidylinositol diphosphate-inositol triphosphate system, and the cyclic GMP system.
Entry Term(s)
Intracellular Second Messengers
Second Messengers
NLM Classification #
QU 120
Public MeSH Note
89
History Note
89
Date Introduced
1989/01/01
Last Updated
2019/05/24
Second Messenger Systems Preferred
Second Messengers Narrower
page delivered in 0.139s