TNF Receptor-Associated Factor 1 MeSH Descriptor Data 2025

MeSH Heading: TNF Receptor-Associated Factor 1
Tree Number(s): D12.644.360.024.500.500; D12.776.157.057.500.500; D12.776.476.024.500.500
Unique ID: D047990
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D047990
Scope Note: A signal transducing tumor necrosis factor receptor associated factor that is involved in TNF RECEPTOR feedback regulation. It is similar in structure and appears to work in conjunction with TNF RECEPTOR-ASSOCIATED FACTOR 2 to inhibit APOPTOSIS.
Entry Version: TNF RECEPT ASSOC FACTOR 1
Entry Term(s): TNF Receptor-Associated Protein 1; TRAF1
Previous Indexing: Proteins (1994-2004)
Public MeSH Note: 2005; TNF RECEPTOR-ASSOCIATED FACTOR 1 was indexed under PROTEINS 1994-2004
History Note: 2005(1994)
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2015/11/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Intracellular Signaling Peptides and Proteins [D12.644.360]
    - Adaptor Proteins, Signal Transducing [D12.644.360.024]
      - Tumor Necrosis Factor Receptor-Associated Peptides and Proteins [D12.644.360.024.500]
        
        CASP8 and FADD-Like Apoptosis Regulating Protein [D12.644.360.024.500.024]
        
        CRADD Signaling Adaptor Protein [D12.644.360.024.500.050]
        
        Edar-Associated Death Domain Protein [D12.644.360.024.500.061]
        
        Fas-Associated Death Domain Protein [D12.644.360.024.500.124]
        
        TNF Receptor-Associated Death Domain Protein [D12.644.360.024.500.249]
        
        TNF Receptor-Associated Factor 1 [D12.644.360.024.500.500]
        
        TNF Receptor-Associated Factor 2 [D12.644.360.024.500.750]
        
        TNF Receptor-Associated Factor 3 [D12.644.360.024.500.875]
        
        TNF Receptor-Associated Factor 4 [D12.644.360.024.500.906]
        
        TNF Receptor-Associated Factor 5 [D12.644.360.024.500.937]
        
        TNF Receptor-Associated Factor 6 [D12.644.360.024.500.968]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Adaptor Proteins, Signal Transducing [D12.776.157.057]
      - Tumor Necrosis Factor Receptor-Associated Peptides and Proteins [D12.776.157.057.500]
        
        CRADD Signaling Adaptor Protein [D12.776.157.057.500.050]
        
        Edar-Associated Death Domain Protein [D12.776.157.057.500.061]
        
        Fas-Associated Death Domain Protein [D12.776.157.057.500.124]
        
        Receptor-Interacting Protein Serine-Threonine Kinases [D12.776.157.057.500.186]
        
        TNF Receptor-Associated Death Domain Protein [D12.776.157.057.500.249]
        
        TNF Receptor-Associated Factor 1 [D12.776.157.057.500.500]
        
        TNF Receptor-Associated Factor 2 [D12.776.157.057.500.750]
        
        TNF Receptor-Associated Factor 3 [D12.776.157.057.500.875]
        
        TNF Receptor-Associated Factor 4 [D12.776.157.057.500.906]
        
        TNF Receptor-Associated Factor 5 [D12.776.157.057.500.937]
        
        TNF Receptor-Associated Factor 6 [D12.776.157.057.500.968]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intracellular Signaling Peptides and Proteins [D12.776.476]
    - Adaptor Proteins, Signal Transducing [D12.776.476.024]
      - Tumor Necrosis Factor Receptor-Associated Peptides and Proteins [D12.776.476.024.500]
        
        CRADD Signaling Adaptor Protein [D12.776.476.024.500.050]
        
        Edar-Associated Death Domain Protein [D12.776.476.024.500.061]
        
        Fas-Associated Death Domain Protein [D12.776.476.024.500.124]
        
        Receptor-Interacting Protein Serine-Threonine Kinases [D12.776.476.024.500.186]
        
        TNF Receptor-Associated Death Domain Protein [D12.776.476.024.500.249]
        
        TNF Receptor-Associated Factor 1 [D12.776.476.024.500.500]
        
        TNF Receptor-Associated Factor 2 [D12.776.476.024.500.750]
        
        TNF Receptor-Associated Factor 3 [D12.776.476.024.500.875]
        
        TNF Receptor-Associated Factor 4 [D12.776.476.024.500.906]
        
        TNF Receptor-Associated Factor 5 [D12.776.476.024.500.937]
        
        TNF Receptor-Associated Factor 6 [D12.776.476.024.500.968]

TNF Receptor-Associated Factor 1 Preferred

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