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The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.
Entry Term(s)
Oncogenesis
Tumorigenesis
NLM Classification #
QZ 203
Previous Indexing
Cell Transformation, Neoplastic (1963-2013)
Public MeSH Note
2014; for TUMORIGENESIS and ONCOGENESIS see CELL TRANSFORMATION, NEOPLASTIC 2012-2013
History Note
2014; for TUMORIGENESIS and ONCOGENESIS see CELL TRANSFORMATION, NEOPLASTIC 2012-2013
The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.