MeSH Browser

MeSH Heading: Protein Kinase C-epsilon
Tree Number(s): D08.811.913.696.620.682.700.725.750; D12.776.476.563.725.750
Unique ID: D051744
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051744
Scope Note: A protein kinase C subtype that was originally characterized as a CALCIUM-independent, serine-threonine kinase that is activated by PHORBOL ESTERS and DIACYLGLYCEROLS. It is targeted to specific cellular compartments in response to extracellular signals that activate G-PROTEIN-COUPLED RECEPTORS; TYROSINE KINASE RECEPTORS; and intracellular protein tyrosine kinase.
Entry Term(s): PKC epsilon; PKC-epsilon Serine Threonine Kinase; Protein Kinase C epsilon
Registry Numbers: EC 2.7.11.13
Public MeSH Note: 2006; PROTEIN KINASE C EPSILON was indexed under PROTEIN KINASE C 1994-2005
History Note: 2006(1994)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0234611
Registry Numbers: EC 2.7.11.13
Scope Note: A protein kinase C subtype that was originally characterized as a CALCIUM-independent, serine-threonine kinase that is activated by PHORBOL ESTERS and DIACYLGLYCEROLS. It is targeted to specific cellular compartments in response to extracellular signals that activate G-PROTEIN-COUPLED RECEPTORS; TYROSINE KINASE RECEPTORS; and intracellular protein tyrosine kinase.
Terms: Protein Kinase C-epsilon Preferred Term
Term UI T264615
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); PKC epsilon
Term UI T264614
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Protein Kinase C epsilon
Term UI T264616
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); PKC-epsilon Serine Threonine Kinase
Term UI T637824
Date04/25/2005
LexicalTag ABX
ThesaurusID NLM (2006)

Protein Kinase C-epsilon MeSH Descriptor Data 2025