MeSH Browser

MeSH Heading: Elafin
Tree Number(s): D12.644.822.437; D12.776.815.437
Unique ID: D053492
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D053492
Scope Note: A secretory proteinase inhibitory protein that was initially purified from human SKIN. It is found in a variety mucosal secretions and is present at high levels in SPUTUM. Elafin may play a role in the innate immunity (IMMUNITY, INNATE) response of the LUNG.
Entry Term(s): Peptidase Inhibitor 3, Skin-derived; Protease Inhibitor 3, Skin-derived; Protease Inhibitor WAP3; Skin-Derived Antileukoproteinase
Pharm Action: Protease Inhibitors
Previous Indexing: Protease Inhibitors (1990-2006)
Public MeSH Note: 2007; ELAFIN was indexed under PROTEINS 2005-2006
History Note: 2007(2005)
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2022/07/12

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0485533
Scope Note: A secretory proteinase inhibitory protein that was initially purified from human SKIN. It is found in a variety mucosal secretions and is present at high levels in SPUTUM. Elafin may play a role in the innate immunity (IMMUNITY, INNATE) response of the LUNG.
Terms: Elafin Preferred Term
Term UI T642184
Date06/06/2005
LexicalTag NON
ThesaurusID NLM (2007); Skin-Derived Antileukoproteinase
Term UI T642183
Date06/06/2005
LexicalTag NON
ThesaurusID NLM (2007); Peptidase Inhibitor 3, Skin-derived
Term UI T663991
Date01/09/2006
LexicalTag NON
ThesaurusID NLM (2007); Protease Inhibitor 3, Skin-derived
Term UI T663992
Date01/09/2006
LexicalTag NON
ThesaurusID NLM (2007); Protease Inhibitor WAP3
Term UI T663993
Date01/09/2006
LexicalTag ABX
ThesaurusID NLM (2007)

Elafin MeSH Descriptor Data 2025