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Tissue Inhibitor of Metalloproteinases MeSH Descriptor Data 2023


MeSH Heading
Tissue Inhibitor of Metalloproteinases
Tree Number(s)
D12.776.815.875
Unique ID
D019714
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019714
Annotation
general or unspecified; prefer specifics
Scope Note
A family of secreted protease inhibitory proteins that regulates the activity of SECRETED MATRIX METALLOENDOPEPTIDASES. They play an important role in modulating the proteolysis of EXTRACELLULAR MATRIX, most notably during tissue remodeling and inflammatory processes.
Entry Version
TISSUE INHIB METALLOPROTEINASES
Entry Term(s)
TIMP Proteins
Tissue Inhibitor of Metalloproteinase
Pharm Action
Matrix Metalloproteinase Inhibitors
Registry Number
0
Previous Indexing
Enzyme Inhibitors (1989-1997)
Glycoproteins (1980-1990)
Public MeSH Note
98; COLLAGENASE INHIBITOR (now TISSUE INHIBITOR OF METALLOPROTEINASES) was indexed under GLYCOPROTEINS 1989-97 & ENZYME INHIBITORS 1980-90
History Note
98; see TISSUE INHIBITOR OF METALLOPROTEINASES (NM) 1980-97
Date Established
1998/01/01
Date of Entry
1997/06/20
Revision Date
2022/07/12
Tissue Inhibitor of Metalloproteinases Preferred
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