MeSH Browser

MeSH Heading: Tissue Inhibitor of Metalloproteinase-3
Tree Number(s): D12.776.815.875.550
Unique ID: D019717
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019717
Scope Note: A member of the family of tissue inhibitor of metalloproteinases. Mutations of the gene for TIMP3 PROTEIN causes Sorsby fundus dystrophy.
Entry Version: TISSUE INHIB METALLOPROTEINASE 3
Entry Term(s): TIMP-3; TIMP-3 Protein; TIMP3 Protein
Pharm Action: Matrix Metalloproteinase Inhibitors
Previous Indexing: Neoplasm Proteins (1992-1995); Proteins (1995-1997)
Public MeSH Note: 1998; TISSUE INHIBITOR OF METALLOPROTEINASE 3 was indexed under PROTEINS 1995-97 & NEOPLASM PROTEINS 1992-1995
History Note: 1998; see TISSUE INHIBITOR OF METALLOPROTEINASE-3 (NM) 1992-1997
Date Established: 1998/01/01
Date of Entry: 1997/06/30
Revision Date: 2022/07/12

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0029273
Scope Note: A member of the family of tissue inhibitor of metalloproteinases. Mutations of the gene for TIMP3 PROTEIN causes Sorsby fundus dystrophy.
Terms: Tissue Inhibitor of Metalloproteinase-3 Preferred Term
Term UI T058649
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1998); TIMP3 Protein
Term UI T627338
Date01/10/2005
LexicalTag ABX
ThesaurusID NLM (2006); TIMP-3 Protein
Term UI T627339
Date01/10/2005
LexicalTag ABX
ThesaurusID NLM (2006); TIMP-3
Term UI T754487
Date07/14/2009
LexicalTag ABB
ThesaurusID NLM (2010)

Tissue Inhibitor of Metalloproteinase-3 MeSH Descriptor Data 2025