MeSH Browser

MeSH Heading: Angiotensin-Converting Enzyme Inhibitors
Tree Number(s): D27.505.519.389.745.085
Unique ID: D000806
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000806
Scope Note: A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
Entry Term(s): ACE Inhibitor; ACE Inhibitors; Ace 1 Inhibitor; Ace I Inhibitors; Ace1 Inhibitor; Ace1 Inhibitors; Angiotensin Converting Enzyme Inhibitor; Angiotensin I-Converting Enzyme Inhibitor; Angiotensin I-Converting Enzyme Inhibitors; Angiotensin-Converting Enzyme Antagonists; Angiotensin-Converting Enzyme Inhibitor; Antagonists, Angiotensin-Converting Enzyme; Antagonists, Kininase II; Inhibitors, ACE; Inhibitors, Angiotensin-Converting Enzyme; Inhibitors, Kininase II; Kininase II Antagonists; Kininase II Inhibitor; Kininase II Inhibitors
Registry Numbers: 0
Previous Indexing: Enzyme Inhibitors (1975-1987); Enzymes/antagonists & inhibitors (1968-1974); Kininase II/antagonists & inhibitors (1973-1987)
Public MeSH Note: 1988; ANGIOTENSIN I-CONVERTING ENZYME INHIBITOR was see TEPROTIDE 1991-1993
History Note: 1988; ANGIOTENSIN I-CONVERTING ENZYME INHIBITOR was see TEPROTIDE 1991-1993
Date Introduced: 1988/01/01
Last Updated: 2026/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Chemical Actions and Uses [D27]
- Pharmacologic Actions [D27.505]
  - Molecular Mechanisms of Pharmacological Action [D27.505.519]
    - Enzyme Inhibitors [D27.505.519.389]
      - Protease Inhibitors [D27.505.519.389.745]
        
        Angiotensin-Converting Enzyme Inhibitors [D27.505.519.389.745.085]
        
        Vasopeptidase Inhibitors [D27.505.519.389.745.085.500]
        
        Cysteine Proteinase Inhibitors [D27.505.519.389.745.325]
        
        Dipeptidyl-Peptidase IV Inhibitors [D27.505.519.389.745.335]
        
        Matrix Metalloproteinase Inhibitors [D27.505.519.389.745.610]
        
        Proteasome Inhibitors [D27.505.519.389.745.705]
        
        Renin Inhibitors [D27.505.519.389.745.753]
        
        Serine Proteinase Inhibitors [D27.505.519.389.745.800]
        
        Viral Protease Inhibitors [D27.505.519.389.745.900]

Angiotensin-Converting Enzyme Inhibitors Preferred

Concept UI: M0001207
Registry Numbers: 0
Scope Note: A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
Terms: Angiotensin-Converting Enzyme Inhibitors Preferred Term
Term UI T002397
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1988); ACE Inhibitor
Term UI T000996730
Date11/15/2019
LexicalTag NON
ThesaurusID NLM (2021); ACE Inhibitors
Term UI T002403
Date04/19/1991
LexicalTag NON
ThesaurusID NLM (1992); Angiotensin Converting Enzyme Inhibitor
Term UI T000996729
Date11/15/2019
LexicalTag NON
ThesaurusID NLM (2021); Angiotensin-Converting Enzyme Antagonists
Term UI T002393
Date05/04/1987
LexicalTag NON
ThesaurusID UNK (19XX); Angiotensin-Converting Enzyme Inhibitor
Term UI T001003200
Date12/19/2019
LexicalTag NON
ThesaurusID NLM (2021); Antagonists, Angiotensin-Converting Enzyme
Term UI T002394
Date04/19/1991
LexicalTag NON
ThesaurusID NLM (1992); Antagonists, Kininase II
Term UI T002398
Date04/19/1991
LexicalTag NON
ThesaurusID NLM (1992); Inhibitors, ACE
Term UI T002402
Date04/19/1991
LexicalTag NON
ThesaurusID NLM (1992); Inhibitors, Angiotensin-Converting Enzyme
Term UI T002396
Date04/19/1991
LexicalTag NON
ThesaurusID NLM (1992); Inhibitors, Kininase II
Term UI T002400
Date05/04/1987
LexicalTag NON
ThesaurusID UNK (19XX); Kininase II Antagonists
Term UI T002399
Date05/04/1987
LexicalTag NON
ThesaurusID UNK (19XX); Kininase II Inhibitor
Term UI T000996732
Date11/15/2019
LexicalTag NON
ThesaurusID NLM (2021); Kininase II Inhibitors
Term UI T002401
Date05/04/1987
LexicalTag NON
ThesaurusID UNK (19XX)

Angiotensin I-Converting Enzyme Inhibitors Narrower

Concept UI: M000768819
Terms: Angiotensin I-Converting Enzyme Inhibitors Preferred Term
Term UI T002395
Date02/08/1993
LexicalTag NON
ThesaurusID NLM (1994); Ace 1 Inhibitor
Term UI T001147402
Date03/17/2025
LexicalTag NON
ThesaurusID NLM (2026); Ace I Inhibitors
Term UI T001147403
Date03/17/2025
LexicalTag NON
ThesaurusID NLM (2026); Ace1 Inhibitor
Term UI T001147416
Date03/17/2025
LexicalTag NON
ThesaurusID NLM (2026); Ace1 Inhibitors
Term UI T001147417
Date03/17/2025
LexicalTag NON
ThesaurusID NLM (2026); Angiotensin I-Converting Enzyme Inhibitor
Term UI T000996731
Date11/15/2019
LexicalTag NON
ThesaurusID NLM (2021)

Angiotensin-Converting Enzyme Inhibitors MeSH Descriptor Data 2026