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Alkylating Agents MeSH Descriptor Data 2025


MeSH Heading
Alkylating Agents
Tree Number(s)
D27.505.519.124
D27.888.569.035
Unique ID
D000477
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000477
Scope Note
Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases.
Entry Term(s)
Alkylating Agent
Alkylator
Alkylators
NLM Classification #
QV 269
Public MeSH Note
66
History Note
66(64)
Date Established
1966/01/01
Date of Entry
1999/01/01
Revision Date
2020/05/27
Alkylating Agents Preferred
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