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gusperimus MeSH Supplementary Concept Data 2023


MeSH Supplementary
gusperimus
Unique ID
C037258
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C037258
Entry Term(s)
1-amino-19-guanidino-11-hydroxy-4,9,12-triazanonadecane-10,13-dione
15-deoxyspergualin
NKT-01
deoxyspergualin
gusperimus trihydrochloride
gusperimus, (+-)-isomer
Pharm Action
Antibiotics, Antineoplastic
Hypoglycemic Agents
Immunosuppressive Agents
Radiation-Protective Agents
Registry Number
UJ0ZJ76DO9
Related Numbers
104317-84-2
57F9XM233R
84937-45-1
85468-01-5
QZS4144IO0
CAS Type 1 Name
Heptanamide, 7-((aminoiminomethyl)amino)-N-(2-((4-((3-aminopropyl)amino)butyl)amino)-1-hydroxy-2-oxoethyl)-
Heading Mapped to
*Guanidines
Frequency
611
Note
synthesized by chemical modification of spergualin; in combination with cyclosporin A prevents diabetes in predisposed NOD mice; structure given in first source; RN given refers to (-)-isomer trihydrochloride
Source
J Antibiot (Tokyo) 1982;35(12):1665
Date of Entry
1983/03/17
Revision Date
2017/10/19
gusperimus Preferred
gusperimus trihydrochloride Narrower
deoxyspergualin Related
gusperimus, (+-)-isomer Narrower
NKT-01 Narrower
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