MeSH Browser

MeSH Supplementary: tanespimycin
Unique ID: C112765
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C112765
Entry Term(s): 17-(allylamino)-17-demethoxy-geldanamycin; 17-(allylamino)-17-demethoxygeldanamycin; 17-AAG; 17-N-allylamino-17-demethoxygeldanamycin; 17-allyl-aminogeldanamycin; 17-allylamino-17-demethoxygeldanamycin; 17-allylamino-17-demethoxygeldanamycin hydroquinone; 17-allylamino-17-demethoxygeldanamycin hydroquinone salt; 17-allylamino-geldanamycin; 17-allylaminogeldanamycin; 17AAG; CNF1010; IPI 493; IPI 504; IPI-493; IPI-504; IPI493; IPI504; NSC 330507; NSC-330507; retaspimycin hydrochloride
Registry Number: 4GY0AVT3L4
Related Numbers: 928Q33Q049
CAS Type 1 Name: ((4E,6E,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-enylamino)-2-azabicyclo(16.3.1)docosa-4,6,10,18,21-pentaen-9-yl) carbamate
Previous Indexing: *QUINONES (1998-2006); RIFABUTIN/*AA (1998-2006)
Heading Mapped to: *Benzoquinones; *Lactams, Macrocyclic
Frequency: 840
Note: an aminoquinone macrocyclic compound; shares the ability of geldanamycin to bind to heat shock protein 90 and GRP94; IPI-504 is the hydroquinone chloride salt which is more water soluble; structure in first source
Source: Cancer Res 1998 Jun 1;58(11):2385-96
Indexing Information: Protein Serine-Threonine Kinases; HSP90 Heat-Shock Proteins
Date of Entry: 1998/07/01
Revision Date: 2020/02/14

Concept UI: M0291469
Registry Number: 4GY0AVT3L4
Related Numbers: 928Q33Q049
Terms: tanespimycin Preferred Term
Term UI T755457
Date07/28/2009
LexicalTag NON
ThesaurusID; 17-(allylamino)-17-demethoxygeldanamycin
Term UI T321474
LexicalTag NON
ThesaurusID NLM (1998); 17AAG
Term UI T431873
Date12/27/2000
LexicalTag NON
ThesaurusID; 17-allyl-aminogeldanamycin
Term UI T465963
Date10/13/2001
LexicalTag NON
ThesaurusID NLM (2001); 17-allylamino-17-demethoxygeldanamycin
Term UI T465964
Date10/13/2001
LexicalTag NON
ThesaurusID; 17-(allylamino)-17-demethoxy-geldanamycin
Term UI T680376
Date08/28/2006
LexicalTag NON
ThesaurusID NLM (2006); 17-N-allylamino-17-demethoxygeldanamycin
Term UI T001006217
Date01/27/2020
LexicalTag NON
ThesaurusID NLM (2020); 17-AAG
Term UI T465962
Date10/13/2001
LexicalTag NON
ThesaurusID NLM (2001)

tanespimycin MeSH Supplementary Concept Data 2023