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tanespimycin MeSH Supplementary Concept Data 2025


MeSH Supplementary
tanespimycin
Unique ID
C112765
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C112765
Entry Term(s)
17-(allylamino)-17-demethoxy-geldanamycin
17-(allylamino)-17-demethoxygeldanamycin
17-AAG
17-N-allylamino-17-demethoxygeldanamycin
17-allyl-aminogeldanamycin
17-allylamino-17-demethoxygeldanamycin
17-allylamino-17-demethoxygeldanamycin hydroquinone
17-allylamino-17-demethoxygeldanamycin hydroquinone salt
17-allylamino-geldanamycin
17-allylaminogeldanamycin
17AAG
CNF1010
IPI 493
IPI 504
IPI-493
IPI-504
IPI493
IPI504
NSC 330507
NSC-330507
retaspimycin hydrochloride
Related Numbers
928Q33Q049
CAS Type 1 Name
((4E,6E,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-enylamino)-2-azabicyclo(16.3.1)docosa-4,6,10,18,21-pentaen-9-yl) carbamate
Previous Indexing
*QUINONES (1998-2006)
RIFABUTIN/*AA (1998-2006)
Heading Mapped to
*Benzoquinones
*Lactams, Macrocyclic
Frequency
840
Note
an aminoquinone macrocyclic compound; shares the ability of geldanamycin to bind to heat shock protein 90 and GRP94; IPI-504 is the hydroquinone chloride salt which is more water soluble; structure in first source
Source
Cancer Res 1998 Jun 1;58(11):2385-96
Indexing Information
Protein Serine-Threonine Kinases
HSP90 Heat-Shock Proteins
Date of Entry
1998/07/01
Revision Date
2020/02/14
tanespimycin Preferred
NSC 330507 Narrower
17-allylaminogeldanamycin Narrower
17-allylamino-17-demethoxygeldanamycin hydroquinone Narrower
IPI 504 Narrower
retaspimycin hydrochloride Narrower
IPI 493 Narrower
CNF1010 Narrower
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