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ximelagatran MeSH Supplementary Concept Data 2022


MeSH Supplementary
ximelagatran
Unique ID
C426686
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C426686
Entry Term(s)
Exanta
H 376 95
H 376-95
glycine, N-((1)1-cyclohexyl-2-((2)-((((4-(amino(hydroxyimino)methyl)phenyl)methyl)amino)carbonyl)-1-azetidinyl)2-oxoethyl)-ethyl ester
glycine, N-((1R)1-cyclohexyl-2-((2S)-((((4-(amino(hydroxyimino)methyl)phenyl)methyl)amino)carbonyl)-1-azetidinyl)2-oxoethyl)-ethyl ester
xi-melagatran
Pharm Action
Antithrombins
Registry Number
49HFB70472
Heading Mapped to
*Azetidines
*Benzylamines
Frequency
388
Note
prodrug (via hydroxylation) of melagatran & a direct thrombin inhibitor; liver toxicity concerns so AZD0837 being developed to replace this
Source
Thromb Res 2001 Feb 1;101(3):171-81
Date of Entry
2001/05/29
Revision Date
2012/11/05
ximelagatran Preferred
Exanta Narrower
H 376 95 Narrower
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