MeSH Browser

MeSH Supplementary: Leukocyte adhesion deficiency type 1
Unique ID: C535887
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C535887
Entry Term(s): Leukocyte Adhesion Deficiency, Type I; Lfa1 Immunodeficiency; Lymphocyte function-associated antigen 1 immunodeficiency
Registry Number: 0
Heading Mapped to: *Leukocyte-Adhesion Deficiency Syndrome
Frequency: 64
Note: An autosomal recessive form of leukocyte adhesion deficiency syndrome that results from a deficiency of the beta-2 integrin subunit (ITGB2 gene) of the leukocyte cell adhesion molecule which is present on the surface of peripheral blood MONONUCLEAR LEUKOCYTES and GRANULOCYTES and mediates cell-cell and cell-EXTRACELLULAR MATRIX adhesion. OMIM: 116920
Date of Entry: 2010/08/25
Revision Date: 2015/08/18

Leukocyte adhesion deficiency type 1 MeSH Supplementary Concept Data 2023