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pevonedistat MeSH Supplementary Concept Data 2023


MeSH Supplementary
pevonedistat
Unique ID
C539933
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C539933
Entry Term(s)
((1S,2S,4R)-4-(4-((1S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate
((1S,2S,4R)-4-(4-((1S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulphamate
4-(4-((1S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl methyl sulfamidate
MLN-4924
MLN4924
Pharm Action
Enzyme Inhibitors
Registry Number
S3AZD8D215
Heading Mapped to
*Cyclopentanes
*Pyrimidines
Frequency
277
Note
a potent and selective inhibitor of NAE (NEDD8-activating enzyme)
Source
Nature. 2009 Apr 9;458(7239):732-6
Date of Entry
2009/04/17
Revision Date
2017/06/26
pevonedistat Preferred
4-(4-((1S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl methyl sulfamidate Related
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