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Lubiprostone MeSH Descriptor Data 2023


MeSH Heading
Lubiprostone
Tree Number(s)
D10.251.355.325.050.500
Unique ID
D000068238
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000068238
Scope Note
Member of a bicyclic fatty acid class of compounds derived from PROSTAGLANDIN E1 involved in chloride channel gating.
Entry Term(s)
Amitiza
Prostan-1-oic acid, 16,16-difluoro-11-hydroxy-9,15-dioxo-, (11alpha)-
RU 0211
RU-0211
RU0211
SPI 0211
SPI-0211
SPI0211
Pharm Action
Chloride Channel Agonists
Registry Number
7662KG2R6K
CAS Type 1 Name
7-((1R,4R,6R,9R)-4-(1,1-difluoropentyl)-4-hydroxy-8-oxo-5-oxabicyclo(4.3.0)non-9-yl)heptanoic acid
Public MeSH Note
2016; LUBIPROSTONE was indexed under ALPROSTADIL 2005-2015
History Note
2016 (2005)
Date Established
2016/01/01
Date of Entry
2015/07/10
Revision Date
2015/07/09
Lubiprostone Preferred
RU 0211 Narrower
Amitiza Broader
SPI 0211 Narrower
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