MeSH Browser

MeSH Heading: Lubiprostone
Tree Number(s): D10.251.355.325.050.500
Unique ID: D000068238
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000068238
Scope Note: Member of a bicyclic fatty acid class of compounds derived from PROSTAGLANDIN E1 involved in chloride channel gating.
Entry Term(s): Amitiza; Prostan-1-oic acid, 16,16-difluoro-11-hydroxy-9,15-dioxo-, (11alpha)-; RU 0211; RU-0211; RU0211; SPI 0211; SPI-0211; SPI0211
Pharm Action: Chloride Channel Agonists
Registry Numbers: 7662KG2R6K; 0
CAS Type 1 Name: 7-((1R,4R,6R,9R)-4-(1,1-difluoropentyl)-4-hydroxy-8-oxo-5-oxabicyclo(4.3.0)non-9-yl)heptanoic acid
Public MeSH Note: 2016; LUBIPROSTONE was indexed under ALPROSTADIL 2005-2015
History Note: 2016 (2005)
Date Established: 2016/01/01
Date of Entry: 2015/07/10
Revision Date: 2015/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Lubiprostone MeSH Descriptor Data 2024