A family of eukaryotic transcription factors that recognize and bind to a highly-conserved cis-regulatory sequence (X-box) within the promoter region of MHC CLASS II GENES. They contain a conserved winged-helix DNA binding domain and function as homo or heterodimers.
Entry Term(s)
RFX Transcription Factors
Public MeSH Note
2017; REGULATORY FACTOR X TRANSCRIPTION FACTORS was indexed under DNA-BINDING PROTEINS and TRANSCRIPTION FACTORS 1988-2016
A family of eukaryotic transcription factors that recognize and bind to a highly-conserved cis-regulatory sequence (X-box) within the promoter region of MHC CLASS II GENES. They contain a conserved winged-helix DNA binding domain and function as homo or heterodimers.
