MeSH Browser

MeSH Heading: NIMA-Related Kinase 1
Tree Number(s): D08.811.913.696.620.682.700.581.500; D12.776.167.457.500; D12.776.476.563.581.500
Unique ID: D000072380
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000072380
Scope Note: A NIMA-related kinase that functions in CELL CYCLE regulation, the control of CILIA assembly, and CENTROSOME duplication. It is activated at G2 PHASE CELL CYCLE CHECKPOINTS in response to DNA DAMAGE.
Entry Term(s): NIMA-Related Protein Kinase 1; Nek1 Kinase; Nek1 Protein Kinase
Registry Numbers: EC 2.7.11.1
Public MeSH Note: 2017; NIMA-RELATED KINASE-1 was indexed under PROTEIN-SERINE-THREONINE KINASES and CELL CYCLE PROTEINS 2004-2016, and under PROTEIN KINASES 1991-2004
History Note: 2017 (1991)
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000617018
Registry Numbers: EC 2.7.11.1
Scope Note: A NIMA-related kinase that functions in CELL CYCLE regulation, the control of CILIA assembly, and CENTROSOME duplication. It is activated at G2 PHASE CELL CYCLE CHECKPOINTS in response to DNA DAMAGE.
Terms: NIMA-Related Kinase 1 Preferred Term
Term UI T000899411
Date04/21/2016
LexicalTag NON
ThesaurusID NLM (2007); NIMA-Related Protein Kinase 1
Term UI T000899403
Date04/21/2016
LexicalTag ACX
ThesaurusID NLM (2017); Nek1 Kinase
Term UI T000899412
Date04/21/2016
LexicalTag NON
ThesaurusID NLM (1991); Nek1 Protein Kinase
Term UI T000899413
Date04/21/2016
LexicalTag NON
ThesaurusID NLM (1991)

NIMA-Related Kinase 1 MeSH Descriptor Data 2025