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Angiopoietin-Like Protein 4 MeSH Descriptor Data 2026


MeSH Heading
Angiopoietin-Like Protein 4
Tree Number(s)
D12.644.276.100.050.400
D12.776.467.100.050.400
D23.529.100.050.400
Unique ID
D000075803
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000075803
Scope Note
A secreted angiopoietin-like protein expressed under hypoxic conditions by ENDOTHELIAL CELLS. It inhibits cell proliferation, cell migration, and tubule formation; the inactive form accumulates in the endothelial EXTRACELLULAR MATRIX, reducing vascular leakage. ANGPTL4 has direct roles in regulating glucose and lipid metabolism, as well as INSULIN SENSITIVITY, and may also function as a regulator of angiogenesis and tumorigenesis.
Entry Term(s)
ANGPTL4 Protein
Angiopoietin-related Protein 4
Registry Numbers
0
Previous Indexing
Angiopoietins (2004-2017)
Blood Proteins (2000-2017)
Public MeSH Note
2022: see ANGIOPOIETIN-LIKE 4 PROTEIN 2018-2021
History Note
2022(2018)
Date Introduced
2018/01/01
Last Updated
2021/06/27
Angiopoietin-Like Protein 4 Preferred
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