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Troglitazone MeSH Descriptor Data 2021


MeSH Heading
Troglitazone
Tree Number(s)
D02.886.675.933.750
D03.383.129.708.933.750
D03.383.663.283.240.612
D03.633.100.150.240.612
Unique ID
D000077288
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077288
Scope Note
A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
Entry Term(s)
5-(4-((6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl-methoxy)benzyl)-2,4-thiazolidinedione) - T
CS 045
CS-045
Prelay
Rezulin
Pharm Action
Hypoglycemic Agents
Registry Number
I66ZZ0ZN0E
Related Numbers
97322-87-7
CAS Type 1 Name
2,4-Thiazolidinedione, 5-((4-((3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy)phenyl)methyl)-
Public MeSH Note
2019; TROGLITAZONE was indexed under CHROMANS and THIAZOLIDINEDIONES 2004-2018; and under THIAZOLES 1988-2003
History Note
2019 (1988)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/02/27
Troglitazone Preferred
CS 045 Narrower
Rezulin Narrower
Prelay Narrower
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