MeSH Browser

MeSH Heading: Glymphatic System
Tree Number(s): A07.521; A08.186.211.150; A15.382.520.075
Unique ID: D000077502
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000077502
Scope Note: A vascular waste clearance system in the brain analogous to the lymphatic system that facilitates transporting of solutes and waste products from CEREBROSPINAL FLUID (CSF) and brain INTERSTITIAL FLUID (ISF). CSF from the SUBARACHNOID SPACE enters the brain periarterial spaces, into the interstitium via channels (e.g., AQUAPORIN 4 PROTEIN) on astrocytic endfeet and exchanges with brain ISF before perivenous drainage of solutes and waste.
Entry Term(s): Brain Perivascular Space; Brain Perivascular Spaces; Glymphatic Clearance System; Glymphatic Pathway; Meningeal Lymphatic Vessel; Meningeal Lymphatic Vessels; Virchow-Robin Space; Virchow-Robin Spaces
Previous Indexing: Lymphatic System (2013-2018)
Public MeSH Note: 2019
History Note: 2019
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2020/05/27

Allowable Qualifiers: abnormalities (AB)

anatomy & histology (AH)

chemistry (CH)

cytology (CY)

diagnostic imaging (DG)

drug effects (DE)

embryology (EM)

enzymology (EN)

growth & development (GD)

immunology (IM)

injuries (IN)

innervation (IR)

metabolism (ME)

microbiology (MI)

parasitology (PS)

pathology (PA)

physiology (PH)

physiopathology (PP)

radiation effects (RE)

surgery (SU)

transplantation (TR)

ultrastructure (UL)

virology (VI)

Concept UI: M000640812
Scope Note: A vascular waste clearance system in the brain analogous to the lymphatic system that facilitates transporting of solutes and waste products from CEREBROSPINAL FLUID (CSF) and brain INTERSTITIAL FLUID (ISF). CSF from the SUBARACHNOID SPACE enters the brain periarterial spaces, into the interstitium via channels (e.g., AQUAPORIN 4 PROTEIN) on astrocytic endfeet and exchanges with brain ISF before perivenous drainage of solutes and waste.
Terms: Glymphatic System Preferred Term
Term UI T000939995
Date02/02/2018
LexicalTag NON
ThesaurusID NLM (2019); Glymphatic Clearance System
Term UI T000939997
Date02/02/2018
LexicalTag NON
ThesaurusID NLM (2019); Glymphatic Pathway
Term UI T000940036
Date02/05/2018
LexicalTag NON
ThesaurusID NLM (2019)

Concept UI: M000640814
Terms: Brain Perivascular Spaces Preferred Term
Term UI T000939998
Date02/02/2018
LexicalTag NON
ThesaurusID NLM (2019); Virchow-Robin Space
Term UI T000997525
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021); Brain Perivascular Space
Term UI T000997527
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021); Virchow-Robin Spaces
Term UI T000939999
Date02/02/2018
LexicalTag EPO
ThesaurusID NLM (2019)

Glymphatic System MeSH Descriptor Data 2025