MeSH Browser

MeSH Heading: Thymalfasin
Tree Number(s): D06.472.910.850.500; D12.644.548.869.500; D12.776.922.500
Unique ID: D000077596
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000077596
Scope Note: A thymus hormone polypeptide found in thymosin fraction 5 (a crude thymus gland extract) but now produced by synthesis. It is used alone or with interferon as an immunomodulator for the treatment of CHRONIC HEPATITIS B and HEPATITIS C. Thymalfasin is also used for the treatment of chemotherapy-induced immunosuppression, and to enhance the efficacy of influenza and hepatitis B vaccines in immunocompromised patients.
Entry Term(s): Thymosin alpha(1); Thymosin alpha1; Zadaxin; alpha1-Thymosin
Pharm Action: Adjuvants, Immunologic
Public MeSH Note: 2019; THYMALFASIN was indexed under THYMOSIN/analogs & derivatives 1984-2018; and under THYMOSIN/analogs 1980-1983
History Note: 2019 (1980)
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/06/19

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0086869
Scope Note: A thymus hormone polypeptide found in thymosin fraction 5 (a crude thymus gland extract) but now produced by synthesis. It is used alone or with interferon as an immunomodulator for the treatment of CHRONIC HEPATITIS B and HEPATITIS C. Thymalfasin is also used for the treatment of chemotherapy-induced immunosuppression, and to enhance the efficacy of influenza and hepatitis B vaccines in immunocompromised patients.
Terms: Thymalfasin Preferred Term
Term UI T000940425
Date02/14/2018
LexicalTag NON
ThesaurusID; alpha1-Thymosin
Term UI T000940426
Date02/14/2018
LexicalTag NON
ThesaurusID NLM (1980); Thymosin alpha(1)
Term UI T000940427
Date02/14/2018
LexicalTag NON
ThesaurusID NLM (1980); Thymosin alpha1
Term UI T000940428
Date02/14/2018
LexicalTag NON
ThesaurusID NLM (1980)

Thymalfasin MeSH Descriptor Data 2025