NLM Logo

Tolvaptan MeSH Descriptor Data 2023


MeSH Heading
Tolvaptan
Tree Number(s)
D03.633.100.079.875
Unique ID
D000077602
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077602
Scope Note
A benzazepine derivative and selective VASOPRESSIN V2 RECEPTOR antagonist that is used to treat euvolemic and hypervolemic HYPONATREMIA. It is also used in the treatment of rapidly progressing AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE to slow the rate of cyst development and renal insufficiency.
Entry Term(s)
7-Chloro-5-hydroxy-1-(2-methyl-4-(2-methylbenzoylamino)benzoyl)2,3,4,5-tetrahydro-1H-1-benzazepine
OPC 41061
OPC-41061
Samsca
Pharm Action
Antidiuretic Hormone Receptor Antagonists
Registry Number
21G72T1950
Related Numbers
150683-30-0
CAS Type 1 Name
Benzamide, N-(4-((7-chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonyl)-3-methylphenyl)-2-methyl-
Public MeSH Note
2019; TOLVAPTAN was indexed under BENZAZEPINES 1999-2019
History Note
2019 (1999)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/04/09
Tolvaptan Preferred
Samsca Narrower
OPC 41061 Narrower
page delivered in 0.16s