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Trabectedin MeSH Descriptor Data 2023


MeSH Heading
Trabectedin
Tree Number(s)
D03.383.246.619
D03.633.100.531.820.781
Unique ID
D000077606
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077606
Scope Note
A complex structure that includes isoquinolines joined by a cyclic ester; it is a DNA-binding agent and guanine N2 alkylator derived from the marine tunicate, Ecteinascidia turbinata. Trabectedin is used for the treatment of advanced soft-tissue SARCOMA, after failure of ANTHRACYCLINES or IFOSFAMIDE drug therapy.
Entry Term(s)
ET 743
ET-743
Ecteinascidin 743
NSC 684766
Yondelis
Pharm Action
Antineoplastic Agents, Alkylating
Registry Number
ID0YZQ2TCP
Related Numbers
114899-77-3
Public MeSH Note
2019; TRABECTIDIN was indexed under DIOXOLES and TETRAHYDROISOQUINOLINES 2007-2018; and under ISOQUINOLINES 1996-2018
History Note
2019 (1996)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/04/09
Trabectedin Preferred
Yondelis Narrower
Ecteinascidin 743 Narrower
NSC 684766 Narrower
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