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Tirapazamine MeSH Descriptor Data 2023


MeSH Heading
Tirapazamine
Tree Number(s)
D03.383.931.867
Unique ID
D000077704
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077704
Scope Note
A triazine derivative that introduces breaks into DNA strands in hypoxic cells, sensitizing tumor cells to the cytotoxic activity of other drugs and radiation.
Entry Term(s)
3-Amino-1,2,4-benzotriazine-1,4-dioxide
NSC 130181
SR 4233
SR-4233
Tirazone
WIN 59075
WIN-59075
Pharm Action
Antineoplastic Agents
Radiation-Sensitizing Agents
Registry Number
1UD32YR59G
Related Numbers
27314-97-2
CAS Type 1 Name
1,2,4-Benzotriazin-3-amine, 1,4-dioxide
Public MeSH Note
2019; TIRAPAZAMINE was indexed under TRIAZINES 1986-2018
History Note
2019 (1986)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/04/09
Tirapazamine Preferred
NSC 130181 Narrower
WIN 59075 Narrower
Tirazone Narrower
SR 4233 Narrower
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