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Tiagabine MeSH Descriptor Data 2025


MeSH Heading
Tiagabine
Tree Number(s)
D03.066.566.500
D03.383.621.566.500
Unique ID
D000078308
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000078308
Scope Note
A nipecotic acid derivative that acts as a GABA uptake inhibitor and anticonvulsant agent. It is used in the treatment of EPILEPSY, for refractory PARTIAL SEIZURES.
Entry Term(s)
(R)-(4,4-bis(3-Methyl-2-thienyl)-3-butenyl)-3-piperidinecarboxylic acid, Hydrochloride
Gabitril
N-(4,4-di(3-Methylthien-2-yl)but-3-enyl)nipecotic acid
NO 328
NO 329
NO-328
NO-329
Tiagabine Hydrochloride
Tiagabine, (S)-isomer
Pharm Action
Anticonvulsants
GABA Uptake Inhibitors
Related Numbers
115103-54-3
115103-55-4
DQH6T6D8OY
CAS Type 1 Name
3-Piperidinecarboxylic acid, 1-(4,4-bis(3-methyl-2-thienyl)-3-buten-1-yl)-, (3R)-
Public MeSH Note
2019; TIAGABINE was indexed under NIPECOTIC ACIDS 1989-2018
History Note
2019 (1989)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/05/21
Tiagabine Preferred
Tiagabine Hydrochloride Narrower
NO 328 Narrower
NO 329 Narrower
Tiagabine, (S)-isomer Narrower
Gabitril Narrower
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