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Acetazolamide MeSH Descriptor Data 2021


MeSH Heading
Acetazolamide
Tree Number(s)
D02.886.675.867.060
D03.383.129.708.867.060
Unique ID
D000086
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000086
Scope Note
One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Entry Term(s)
Acetadiazol
Acetazolam
Acetazolamide Sodium, (Sterile)
Acetazolamide, Monosodium Salt
Ak-Zol
Apo-Acetazolamide
Diacarb
Diamox
Diuramide
Défiltran
Edemox
Glauconox
Glaupax
Huma-Zolamide
Pharm Action
Anticonvulsants
Carbonic Anhydrase Inhibitors
Diuretics
Registry Number
O3FX965V0I
Related Numbers
1424-27-7
59-66-5
CAS Type 1 Name
Acetamide, N-(5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl)-
Date Established
1966/01/01
Date of Entry
1999/01/01
Revision Date
2016/06/24
Acetazolamide Preferred
Acetazolam Narrower
Acetazolamide Sodium, (Sterile) Narrower
Acetazolamide, Monosodium Salt Narrower
Ak-Zol Narrower
Apo-Acetazolamide Narrower
Diacarb Narrower
Diamox Narrower
Diuramide Narrower
Défiltran Narrower
Edemox Narrower
Glauconox Narrower
Glaupax Narrower
Huma-Zolamide Narrower
Acetadiazol Narrower
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