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T-Cell Exhaustion MeSH Descriptor Data 2023


MeSH Heading
T-Cell Exhaustion
Tree Number(s)
G12.819
Unique ID
D000094383
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000094383
Scope Note
Progressive deterioration of T-cell function due to chronic antigen stimulation and inflammatory signals, e.g., CHRONIC INFECTION and CANCER. T-cell exhaustion is characterized by weakened immune system, e.g., dysfunctional MEMORY T CELLS differentiation and EPIGENETIC REPRESSION of IMMUNOLOGIC MEMORY effector functions.
Entry Term(s)
T-Cell Senescence
See Also
Lymphocyte Depletion
Public MeSH Note
2023
History Note
2023
Date Established
2023/01/01
Date of Entry
2022/07/12
Revision Date
2022/07/12
T-Cell Exhaustion Preferred
T-Cell Senescence Related
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