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Integrated Stress Response MeSH Descriptor Data 2026


MeSH Heading
Integrated Stress Response
Tree Number(s)
G07.775.563
Unique ID
D000099121
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000099121
Scope Note
A signaling pathway that enables cells to adapt to various stressors by modulating protein synthesis. It is initiated by the activation of specific PROTEIN KINASES (e.g., PERK, GCN2, PKR, and HRI) in response to distinct stress signals, including amino acid deprivation, VIRAL INFECTIONS, and OXIDATIVE STRESS.
Entry Term(s)
Integrated Stress Response (ISR)
Previous Indexing
PI scattered
Public MeSH Note
2026
History Note
2026
Date Introduced
2026/01/01
Last Updated
2026/01/01
Integrated Stress Response Preferred
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