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An enzyme that catalyzes the formation of CoA derivatives from ATP, acetate, and CoA to form AMP, pyrophosphate, and acetyl CoA. It acts also on propionates and acrylates. EC 6.2.1.1.
Entry Term(s)
Acetate Thiokinase
Acetothiokinase
Acetyl Activating Enzyme
Acetyl CoA Synthetase
Acetyl Coenzyme A Synthetase
Registry Numbers
EC 6.2.1.1
Related Numbers
9012-31-1
CAS Type 1 Name
Acetate:CoA ligase (AMP-forming)
Previous Indexing
Acetyl Coenzyme A (1974-1975)
Coenzyme A Synthetases (1974-1975)
Public MeSH Note
95; was ACETYL COENZYME A SYNTHETASE 1991-94; was see under COENZYME A SYNTHETASES 1976-90
Online Note
use ACETATE-COA LIGASE to search ACETYL COENZYME A SYNTHETASE 1991-94
History Note
95; was ACETYL COENZYME A SYNTHETASE 1991-94; was see under COENZYME A SYNTHETASES 1976-90
An enzyme that catalyzes the formation of CoA derivatives from ATP, acetate, and CoA to form AMP, pyrophosphate, and acetyl CoA. It acts also on propionates and acrylates. EC 6.2.1.1.