MeSH Browser

MeSH Heading: Acidosis, Renal Tubular
Tree Number(s): C12.050.351.968.419.815.093; C12.200.777.419.815.093; C12.950.419.815.093; C16.320.831.093; C18.452.076.176.210
Unique ID: D000141
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000141
Scope Note: A group of genetic disorders of the KIDNEY TUBULES characterized by the accumulation of metabolically produced acids with elevated plasma chloride, hyperchloremic metabolic ACIDOSIS. Defective renal acidification of URINE (proximal tubules) or low renal acid excretion (distal tubules) can lead to complications such as HYPOKALEMIA, hypercalcinuria with NEPHROLITHIASIS and NEPHROCALCINOSIS, and RICKETS.
Entry Term(s): Acidosis, Renal Tubular, Type I; Acidosis, Renal Tubular, Type II; Autosomal Dominant Distal Renal Tubular Acidosis; Classic Distal Renal Tubular Acidosis; Distal Renal Tubular Acidosis; Proximal Renal Tubular Acidosis; RTA, Classic Type; RTA, Distal Type, Autosomal Dominant; RTA, Gradient Type; RTA, Proximal Type; Renal Tubular Acidosis; Renal Tubular Acidosis 1; Renal Tubular Acidosis I; Renal Tubular Acidosis II; Renal Tubular Acidosis, Distal, Autosomal Dominant; Renal Tubular Acidosis, Proximal; Renal Tubular Acidosis, Proximal, with Ocular Abnormalities; Renal Tubular Acidosis, Type I; Renal Tubular Acidosis, Type II; Type I Renal Tubular Acidosis; Type II Renal Tubular Acidosis
NLM Classification #: WJ 301
Public MeSH Note: 65
History Note: 65
Date Established: 1965/01/01
Date of Entry: 1999/01/01
Revision Date: 2021/06/30

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Urogenital Diseases [C12]
- Female Urogenital Diseases and Pregnancy Complications [C12.050]
  - Female Urogenital Diseases [C12.050.351]
    - Urologic Diseases [C12.050.351.968]
      - Kidney Diseases [C12.050.351.968.419]
        
        Renal Tubular Transport, Inborn Errors [C12.050.351.968.419.815]
        
        Acidosis, Renal Tubular [C12.050.351.968.419.815.093]
        
        Bartter Syndrome [C12.050.351.968.419.815.279]
        
        Dent Disease [C12.050.351.968.419.815.364]
        
        Fanconi Syndrome [C12.050.351.968.419.815.450]
        
        Gitelman Syndrome [C12.050.351.968.419.815.491]
        
        Glycosuria, Renal [C12.050.351.968.419.815.532]
        
        Hypophosphatemia, Familial [C12.050.351.968.419.815.647]
        
        Liddle Syndrome [C12.050.351.968.419.815.683]
        
        Oculocerebrorenal Syndrome [C12.050.351.968.419.815.720]
        
        Pseudohypoaldosteronism [C12.050.351.968.419.815.770]
        
        Renal Aminoacidurias [C12.050.351.968.419.815.885]

Urogenital Diseases [C12]
- Male Urogenital Diseases [C12.200]
  - Urologic Diseases [C12.200.777]
    - Kidney Diseases [C12.200.777.419]
      - Renal Tubular Transport, Inborn Errors [C12.200.777.419.815]
        
        Acidosis, Renal Tubular [C12.200.777.419.815.093]
        
        Bartter Syndrome [C12.200.777.419.815.279]
        
        Dent Disease [C12.200.777.419.815.364]
        
        Fanconi Syndrome [C12.200.777.419.815.450]
        
        Gitelman Syndrome [C12.200.777.419.815.491]
        
        Glycosuria, Renal [C12.200.777.419.815.532]
        
        Hypophosphatemia, Familial [C12.200.777.419.815.647]
        
        Liddle Syndrome [C12.200.777.419.815.683]
        
        Oculocerebrorenal Syndrome [C12.200.777.419.815.720]
        
        Pseudohypoaldosteronism [C12.200.777.419.815.770]
        
        Renal Aminoacidurias [C12.200.777.419.815.885]

Urogenital Diseases [C12]
- Urologic Diseases [C12.950]
  - Kidney Diseases [C12.950.419]
    - Renal Tubular Transport, Inborn Errors [C12.950.419.815]

Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
  - Renal Tubular Transport, Inborn Errors [C16.320.831]

Nutritional and Metabolic Diseases [C18]
- Metabolic Diseases [C18.452]
  - Acid-Base Imbalance [C18.452.076]
    - Acidosis [C18.452.076.176]

Acidosis, Renal Tubular Preferred

Renal Tubular Acidosis, Type II Narrower

Concept UI: M0000217
Scope Note: The genetic defect is in the sodium bicarbonate cotransporter gene SLC4A4 resulting in impaired reabsorption of bicarbonate ions in the proximal renal tubules and bicarbonate-wasting.
Terms: Renal Tubular Acidosis, Type II Preferred Term
Term UI T657448
Date11/01/2005
LexicalTag NON
ThesaurusID NLM (2007); Acidosis, Renal Tubular, Type II
Term UI T000407
Date05/19/1997
LexicalTag NON
ThesaurusID NLM (1998); Type II Renal Tubular Acidosis
Term UI T000408
Date05/19/1997
LexicalTag NON
ThesaurusID NLM (1998); RTA, Proximal Type
Term UI T823116
Date06/07/2012
LexicalTag ABX
ThesaurusID OMIM (2013); Renal Tubular Acidosis, Proximal, with Ocular Abnormalities
Term UI T657449
Date11/01/2005
LexicalTag NON
ThesaurusID NLM (2007); Renal Tubular Acidosis, Proximal
Term UI T812215
Date11/15/2011
LexicalTag NON
ThesaurusID OMIM (2013); Renal Tubular Acidosis II
Term UI T823115
Date06/07/2012
LexicalTag NON
ThesaurusID OMIM (2013); Proximal Renal Tubular Acidosis
Term UI T000406
Date05/19/1997
LexicalTag NON
ThesaurusID NLM (1998)

Renal Tubular Acidosis, Type I Narrower

Acidosis, Renal Tubular MeSH Descriptor Data 2023