MeSH Browser

MeSH Heading: Adrenergic alpha-Antagonists
Tree Number(s): D27.505.519.625.050.200.100; D27.505.696.577.050.200.100
Unique ID: D000317
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000317
Annotation: general or unspecified; prefer specifics; do not confuse with ADRENERGIC ALPHA-AGONISTS
Scope Note: Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
Entry Version: ADREN ALPHA ANTAG
Entry Term(s): Adrenergic alpha-Blockers; Adrenergic alpha-Receptor Blockaders; alpha-Adrenergic Antagonists; alpha-Adrenergic Blockers; alpha-Adrenergic Blocking Agents; alpha-Adrenergic Receptor Blockaders; alpha-Blockers, Adrenergic
NLM Classification #: QV 132
Previous Indexing: Sympatholytics (1966-1968)
Public MeSH Note: 95; was ADRENERGIC ALPHA RECEPTOR BLOCKADERS 1973-94
Online Note: use ADRENERGIC ALPHA-ANTAGONISTS to search ADRENERGIC ALPHA RECEPTOR BLOCKADERS 1969-94 (as Prov 1969-72)
History Note: 95; was ADRENERGIC ALPHA RECEPTOR BLOCKADERS 1969-94 (Prov 1969-72)
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/06/14

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0000493
Scope Note: Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
Terms: Adrenergic alpha-Antagonists Preferred Term
Term UI T001035
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1969); alpha-Adrenergic Receptor Blockaders
Term UI T001029
Date03/29/1974
LexicalTag NON
ThesaurusID UNK (19XX); Adrenergic alpha-Receptor Blockaders
Term UI T001030
Date02/02/1994
LexicalTag NON
ThesaurusID NLM (1995); alpha-Adrenergic Blocking Agents
Term UI T001031
Date04/17/1989
LexicalTag NON
ThesaurusID IOM (1990); Adrenergic alpha-Blockers
Term UI T001032
Date02/02/1994
LexicalTag NON
ThesaurusID NLM (1995); alpha-Adrenergic Blockers
Term UI T001033
Date03/14/1994
LexicalTag NON
ThesaurusID NLM (1995); alpha-Adrenergic Antagonists
Term UI T000941483
Date03/23/2018
LexicalTag NON
ThesaurusID NLM (2019); alpha-Blockers, Adrenergic
Term UI T001034
Date04/17/1989
LexicalTag NON
ThesaurusID IOM (1990)

Adrenergic alpha-Antagonists MeSH Descriptor Data 2025