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Anesthetics, Local MeSH Descriptor Data 2023


MeSH Heading
Anesthetics, Local
Tree Number(s)
D27.505.696.277.100.200
D27.505.696.663.850.025
D27.505.954.427.210.100.200
Unique ID
D000779
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000779
Annotation
see note at ANESTHETICS
Scope Note
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.
Entry Term(s)
Anesthetics, Conduction-Blocking
Anesthetics, Topical
Conduction-Blocking Anesthetics
Local Anesthetic
Registry Number
0
NLM Classification #
QV 110
Date Established
1966/01/01
Date of Entry
1999/01/01
Revision Date
2020/05/27
Anesthetics, Local Preferred
Anesthetics, Topical Narrower
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