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Argininosuccinate Synthase MeSH Descriptor Data 2026


MeSH Heading
Argininosuccinate Synthase
Tree Number(s)
D08.811.464.259.300
Unique ID
D001124
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D001124
Annotation
/defic: consider also CITRULLINEMIA
Scope Note
An enzyme of the urea cycle that catalyzes the formation of argininosuccinic acid from citrulline and aspartic acid in the presence of ATP. Absence or deficiency of this enzyme causes the metabolic disease CITRULLINEMIA in humans. EC 6.3.4.5.
Entry Term(s)
Argininosuccinate Synthetase
Registry Numbers
EC 6.3.4.5
Related Numbers
9023-58-9
CAS Type 1 Name
L-Citrulline:L-aspartate ligase (AMP-forming)
Previous Indexing
Arginine (1973-1974)
Ligases (1973-1974)
Succinates (1973-1974)
See Also
Citrullinemia
Public MeSH Note
98; see ARGININOSUCCINATE SYNTHETASE 1991-97; see LIGASES 1975-90
History Note
98(75)
Date Introduced
1991/01/01
Last Updated
2003/07/09
Argininosuccinate Synthase Preferred
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