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Baclofen MeSH Descriptor Data 2023


MeSH Heading
Baclofen
Tree Number(s)
D02.241.081.114.500.350.100
Unique ID
D001418
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D001418
Scope Note
A GAMMA-AMINOBUTYRIC ACID derivative that is a specific agonist of GABA-B RECEPTORS. It is used in the treatment of MUSCLE SPASTICITY, especially that due to SPINAL CORD INJURIES. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission.
Entry Term(s)
Apo-Baclofen
Atrofen
Ba-34,647
Ba-34647
Baclofen AWD
Baclofène-Irex
Baclophen
Baclospas
CIBA-34,647-BA
Chlorophenyl GABA
Clofen
Gen-Baclofen
Genpharm
Lebic
Lioresal
Liorésal
Nu-Baclo
PCP-GABA
PMS-Baclofen
beta-(Aminomethyl)-4-chlorobenzenepropanoic Acid
beta-(p-Chlorophenyl)-gamma-aminobutyric Acid
Pharm Action
Muscle Relaxants, Central
GABA-B Receptor Agonists
Registry Number
H789N3FKE8
Related Numbers
1134-47-0
CAS Type 1 Name
Benzenepropanoic acid, beta-(aminomethyl)-4-chloro-
NLM Classification #
QV 140
Previous Indexing
Aminobutyric Acids (1972-1974)
Chlorobenzenes (1974)
Public MeSH Note
80; was see under AMINOBUTYRIC ACIDS 1975-79
History Note
80(75); was see under AMINOBUTYRIC ACIDS 1975-79
Date Established
1980/01/01
Date of Entry
1974/11/11
Revision Date
2016/07/05
Baclofen Preferred
Clofen Narrower
Gen-Baclofen Narrower
Apo-Baclofen Narrower
Atrofen Narrower
Baclofène-Irex Narrower
Baclofen AWD Narrower
Lebic Narrower
Lioresal Narrower
Nu-Baclo Narrower
PMS-Baclofen Narrower
Baclospas Narrower
Ba-34,647 Narrower
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