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Bicuculline MeSH Descriptor Data 2023


MeSH Heading
Bicuculline
Tree Number(s)
D03.132.098.077
D03.633.100.531.085.077
Unique ID
D001640
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D001640
Scope Note
An isoquinoline alkaloid obtained from Dicentra cucullaria and other plants. It is a competitive antagonist for GABA-A receptors.
Entry Term(s)
6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)furo(3,4-e)1,3-benzodioxol-8(6H)one
Pharm Action
Convulsants
GABA-A Receptor Antagonists
Registry Number
Y37615DVKC
Related Numbers
485-49-4
CAS Type 1 Name
Furo(3,4-e)-1,3-benzodioxol-8(6H)-one, 6-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (R-(R*,S*))-
NLM Classification #
QV 103
Previous Indexing
Alkaloids (1972-1974)
Dioxoles (1972-1974)
Isoquinolines (1971-1974)
Public MeSH Note
80; was see under ISOQUINOLINES 1975-79
History Note
80(75); was see under ISOQUINOLINES 1975-79
Date Established
1980/01/01
Date of Entry
1974/11/11
Revision Date
2016/05/27
Bicuculline Preferred
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