MeSH Browser

MeSH Heading: Cystathionine gamma-Lyase
Tree Number(s): D08.811.520.300.250
Unique ID: D003542
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D003542
Annotation: /defic: consider also CYSTATHIONINE /‌urine (IM) + AMINO ACID METABOLISM, INBORN ERRORS (IM)
Scope Note: A multifunctional pyridoxal phosphate enzyme. In the final step in the biosynthesis of cysteine it catalyzes the cleavage of cystathionine to yield cysteine, ammonia, and 2-ketobutyrate. EC 4.4.1.1.
Entry Term(s): Cystathionase; Cysteine Desulfhydrase; Cystine Desulfhydrase; Cystine Desulfohydrolase; Homoserine Deaminase; Homoserine Dehydratase; gamma-Cystathionase
Related Numbers: 9012-96-8
CAS Type 1 Name: L-Cystathionine cysteine-lyase (deaminating)
Previous Indexing: Cysteine (1973-1974); Homoserine (1973-1974); Lyases (1973-1974)
Public MeSH Note: 91; was see under LYASES 1975-90
History Note: 91(75); was see under LYASES 1975-90
Date Established: 1991/01/01
Date of Entry: 1974/11/11
Revision Date: 2003/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0005534
Related Numbers: 9012-96-8
Scope Note: A multifunctional pyridoxal phosphate enzyme. In the final step in the biosynthesis of cysteine it catalyzes the cleavage of cystathionine to yield cysteine, ammonia, and 2-ketobutyrate. EC 4.4.1.1.
Terms: Cystathionine gamma-Lyase Preferred Term
Term UI T010272
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1975); gamma-Cystathionase
Term UI T010275
Date05/17/1976
LexicalTag NON
ThesaurusID UNK (19XX); Homoserine Deaminase
Term UI T010276
Date11/11/1974
LexicalTag NON
ThesaurusID UNK (19XX); Homoserine Dehydratase
Term UI T010277
Date11/11/1974
LexicalTag NON
ThesaurusID UNK (19XX); Cysteine Desulfhydrase
Term UI T010278
Date11/11/1974
LexicalTag NON
ThesaurusID UNK (19XX); Cystathionase
Term UI T010271
Date11/11/1974
LexicalTag NON
ThesaurusID UNK (19XX); Cystine Desulfohydrolase
Term UI T010274
Date02/08/1989
LexicalTag NON
ThesaurusID NLM (1989); Cystine Desulfhydrase
Term UI T010273
Date11/11/1974
LexicalTag NON
ThesaurusID UNK (19XX)

Cystathionine gamma-Lyase MeSH Descriptor Data 2025