MeSH Browser

MeSH Heading: Demecolcine
Tree Number(s): D03.132.225.374
Unique ID: D003703
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D003703
Annotation: /biosyn permitted if by plant
Scope Note: An alkaloid isolated from Colchicum autumnale L. and used as an antineoplastic.
Entry Term(s): Colcemid; Colcemide; Colchamine; Demecolcine, (+-)-Isomer
Pharm Action: Antineoplastic Agents, Phytogenic
Tubulin Modulators
Related Numbers: 102491-77-0; 477-30-5
CAS Type 1 Name: Benzo(a)heptalen-9(5H)-one, 6,7-dihydro-1,2,3,10-tetramethoxy-7-(methylamino)-, (S)-
Previous Indexing: Alkaloids (1966-1971); Antineoplastic Agents (1966-1971); Colchicine (1966-1971)
Public MeSH Note: 73
History Note: 73(72)
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Demecolcine MeSH Descriptor Data 2025